Welcome to Talia Neal-Walthall
390510

Welcome to Talia Neal-Walthall

We are pleased to welcome Talia Neal-Walthall to ECETOC as a secondee. Talia joins us to work on topics related to exposure, an area central to much of our current scientific programme. She will be wi...
September 2026 news from the Sec Gen
390509

September 2026 news from the Sec Gen

Dear members and colleagues,As we move through the year, there is a good deal to share. This has been a busy period for ECETOC, with changes to our team, our governance, and the work ahead. Let me...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
TRA Task Force – Worker branch

TRA Task Force – Worker branch

Why? The Worker TRA Task Force has been active since 2019, delivering projects that advance the scientific basis of the Worker Targeted Risk Assessment (TRA) tool. Its overarching objective is to e...
Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Why?Regulatory assessment of immunotoxic properties of chemicals is a complex and challenging task​ Limited regulatory guidance exists​ Lack of industry and regulatory knowledge​...
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....

Endocrine DisruptorsWildlife impacts

Publications

TR 130: The ECETOC Seven Steps for the Identification of Endocrine Disrupting Properties (ECETOC 7SI-ED)
378049

TR 130: The ECETOC Seven Steps for the Identification of Endocrine Disrupting Properties (ECETOC 7SI-ED)

The ECETOC 7SI-ED is recommended as a tool to assess whether or not a substance possesses endocrine disrupting properties. It is based on robust scientific principles and has been designed to be pract...
Workshop Report no.30: The Role of Epigenetics in Reproductive Toxicity
378005

Workshop Report no.30: The Role of Epigenetics in Reproductive Toxicity

This workshop explored the current state of the science on epigenetics and its role in reproductive toxicity. Experts from a range of scientific disciplines met over two days to share knowledge and br...
Workshop Report 27 – Expert Panel to Better Understand Endocrine Disrupter Low Doses Effects
377429

Workshop Report 27 – Expert Panel to Better Understand Endocrine Disrupter Low Doses Effects

SUMMARY1. This expert panel was convened by ECETOC to discuss the issue of so-called low dose effects of endocrine disrupting chemicals (EDC), and to propose a possible research programme to throw...
377415

Workshop Report 21 – Risk Assessment of Endocrine Disrupting Chemicals

WR 21 : Risk Assessment of Endocrine Disrupting Chemicals | November 2011WR 21 Risk Assessment of Endocrine Disrupting Chemicals 9-10 May 2011, FlorenceISSN-2078-7200-21 (print) ISSN-2078-721...
377756

TR 106 – Guidance on Identifying Endocrine Disrupting Effects

TR 106 : Guidance on Identifying Endocrine Disrupting Effects | June 2009 Recent revision of the European directive on plant protection products (Directive 91/414/EEC) and new regulations concerning...
377431

Workshop Report 16 – Guidance on Interpreting Endocrine Disrupting Effects + Addendum

WR 16 and Addendum : Guidance on Interpreting Endocrine Disrupting Effects and Addendum | October 2009 Please note that this version of the report includes the addendum that was previously published...

Task Forces

Population relevance for NTOs per EU Endocrine Disruption Criteria – Expert Group

Population relevance for NTOs per EU Endocrine Disruption Criteria – Expert Group

Why? Technical guidance is still missing in response to EU scientific criteria for the determination of endocrine disrupting (ED) properties (ECHA & EFSA, 2018), to identify whether observed ad...
Substances that activate various liver receptors as endocrine disruptors

Substances that activate various liver receptors as endocrine disruptors

Why? The current development of NAMs in the field of endocrine disruption (ED) is very active as the concept of ED is evolving in various areas of toxicology including liver toxicity/xenobiotic met...