Part 1 sets out the fundamental elements, from problem formulation to risk characterisation.Brussels, 22 July 2026. The ECETOC Plastic Additives Task Force has published the first of two peer...
Dear colleagues and friends,As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Why?REACH restriction: SPM use restricted; emissions reporting required by May 2027.
Gap: No analytical methods available to measure SPM emissions.
Solution: Draft SPERC-based approac...
Why?Validation of NAMs is often overlooked despite its importance for regulatory use.
Traditional validation methods are less suitable for NAMs, which focus on key events rather than apical...
The ECETOC 7SI-ED is recommended as a tool to assess whether or not a substance possesses endocrine disrupting properties. It is based on robust scientific principles and has been designed to be pract...
This workshop explored the current state of the science on epigenetics and its role in reproductive toxicity. Experts from a range of scientific disciplines met over two days to share knowledge and br...
SUMMARY1. This expert panel was convened by ECETOC to discuss the issue of so-called low dose effects of endocrine disrupting chemicals (EDC), and to propose a possible research programme to throw...
TR 106 : Guidance on Identifying Endocrine Disrupting Effects | June 2009
Recent revision of the European directive on plant protection products (Directive 91/414/EEC) and new regulations concerning...
WR 16 and Addendum : Guidance on Interpreting Endocrine Disrupting Effects and Addendum | October 2009
Please note that this version of the report includes the addendum that was previously published...
Why?
Technical guidance is still missing in response to EU scientific criteria for the determination of endocrine disrupting (ED) properties (ECHA & EFSA, 2018), to identify whether observed ad...
Why?
The current development of NAMs in the field of endocrine disruption (ED) is very active as the concept of ED is evolving in various areas of toxicology including liver toxicity/xenobiotic met...
